Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2010 Aug;105(8):1416-21.
doi: 10.1111/j.1360-0443.2010.02978.x. Epub 2010 Jun 7.

Alcohol use and non-adherence to antiretroviral therapy in HIV-infected patients in West Africa

Antoine Jaquet  1 , Didier K Ekouevi, Jules Bashi, Maiga Aboubakrine, Eugène Messou, Moussa Maiga, Hamar Alassane Traore, Marcel Djimon Zannou, Calixte Guehi, Franck Olivier Ba-Gomis, Albert Minga, Gérard Allou, Serge Paul Eholie, Emmanuel Bissagnene, Annie J Sasco, Francois Dabis
Affiliations
Multicenter Study

Alcohol use and non-adherence to antiretroviral therapy in HIV-infected patients in West Africa

Antoine Jaquet et al. Addiction. 2010 Aug.

Abstract

Aim: To investigate the association between alcohol use and adherence to highly active antiretroviral treatment (HAART) among human immunodeficiency virus (HIV)-infected patients in sub-Saharan Africa.

Design and setting: Cross-sectional survey conducted in eight adult HIV treatment centres from Benin, Côte d'Ivoire and Mali. Participants and measurements During a 4-week period, health workers administered the Alcohol Use Disorders Identification Test to HAART-treated patients and assessed treatment adherence using the AIDS Clinical Trials Group follow-up questionnaire.

Findings: A total of 2920 patients were enrolled with a median age of 38 years [interquartile range (IQR) 32-45 years] and a median duration on HAART of 3 years (IQR 1-4 years). Overall, 91.8% of patients were identified as adherent to HAART. Non-adherence was associated with current drinking [odds ratio (OR) 1.4; 95% confidence interval (CI) 1.1-2.0], hazardous drinking (OR 4.7; 95% CI 2.6-8.6) and was associated inversely with a history of counselling on adherence (OR 0.7; 95% CI 0.5-0.9).

Conclusions: Alcohol consumption and hazardous drinking is associated with non-adherence to HAART among HIV-infected patients from West Africa. Adult HIV care programmes should integrate programmes to reduce hazardous and harmful drinking.

PubMed Disclaimer

References

    1. Braithwaite RS, McGinnis KA, Conigliaro J, Maisto SA, Crystal S, Day N, et al. A temporal and dose-response association between alcohol consumption and medication adherence among veterans in care. Alcohol Clin Exp Res. 2005;29(7):1190–7. Epub 2005/07/28. - PubMed
    1. Kleeberger CA, Phair JP, Strathdee SA, Detels R, Kingsley L, Jacobson LP. Determinants of heterogeneous adherence to HIV-antiretroviral therapies in the Multicenter AIDS Cohort Study. J Acquir Immune Defic Syndr. 2001;26(1):82–92. Epub 2001/02/15. - PubMed
    1. Lucas GM, Gebo KA, Chaisson RE, Moore RD. Longitudinal assessment of the effects of drug and alcohol abuse on HIV-1 treatment outcomes in an urban clinic. AIDS. 2002;16(5):767–74. Epub 2002/04/20. - PubMed
    1. Tucker JS, Burnam MA, Sherbourne CD, Kung FY, Gifford AL. Substance use and mental health correlates of nonadherence to antiretroviral medications in a sample of patients with human immunodeficiency virus infection. Am J Med. 2003;114(7):573–80. Epub 2003/05/20. - PubMed
    1. Clausen T, Rossow I, Naidoo N, Kowal P. Diverse alcohol drinking patterns in 20 African countries. Addiction. 2009;104(7):1147–54. Epub 2009/05/12. - PubMed

Publication types

Substances