Tumor-initiating cells: an influential paradigm for xenograft research
- PMID: 20530515
- PMCID: PMC2940644
- DOI: 10.1093/neuonc/noq053
Tumor-initiating cells: an influential paradigm for xenograft research
Comment on
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A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo.Neuro Oncol. 2010 Jun;12(6):580-94. doi: 10.1093/neuonc/nop056. Epub 2010 Feb 8. Neuro Oncol. 2010. PMID: 20511191 Free PMC article.
References
-
- Krigman MR, Manueldis EE. Distribution of fluorescent tracers in heterologously transplanted intracerebral tumors. Cancer Res. 1964;24:1749–1759. - PubMed
-
- Rana MW, Pinkerton H, Thornton H, Nagy D. Heterotransplantation of human glioblastoma multiforme and meningioma to nude mice. Proc Soc Exp Biol Med. 1977;155:85–88. - PubMed
-
- Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB. Identification of human brain tumour initiating cells. Nature. 2004;432:396–401. - PubMed
-
- Yu L, Baxter PA, Voicu H, Gurusiddappa S, Zhao Y, Adesina A, Man TK, Shu Q, Zhang Y-J, Zhao X-M, Su JM, Perlaky L, Dauser R, Chintagumpala M, Lau CC, Blaney SM, Rao PH, Leung H-CE, Li XN. A clinical relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo. Neuro-Oncology. 2010;12:580–594. - PMC - PubMed
-
- Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006;444:756–760. - PubMed
