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. 2009 Oct;26(4):142-5.
doi: 10.4103/0970-2113.56352.

An unusual presentation of immotile-cilia syndrome with azoospermia: Case report and literature review

Ramakant Dixit  1 , Kalpana Dixit, Savita Jindal, K V Shah
Affiliations

An unusual presentation of immotile-cilia syndrome with azoospermia: Case report and literature review

Ramakant Dixit et al. Lung India. 2009 Oct.

Abstract

Immotile-cilia syndrome is a rare disorder characterized by chronic recurrent sino-pulmonary infection, impaired tracheobronchial clearance, situs inversus in about 50% of cases, and living but immotile spermatozoa of normal morphology in semen analysis. In this report, we describe an unusual presentation of immotile-cilia syndrome with azoospermia in a 32-year-old male patient. The diagnosis was based on history of recurrent respiratory tract infection, bronchiectasis, maxillary sinusitis, hypoplasia of frontal sinuses, dextrocardia with situs inversus, impaired nasal mucociliary clearance, etc. Semen analysis revealed azoospermia without any evidence of obstruction in epididymides or vas deference. Normal spermatogenesis was seen on testicular biopsy.

Keywords: Azoospermia; bronchiectasis; immotile-cilia syndrome; situs inversus.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
X-ray paranasal sinus showing maxillary sinusitis and bilateral hypoplastic frontal sinuses
Figure 2
Figure 2
X-ray chest, PA view, showing dextrocardia and inhomogeneous infiltrate at both the lower zones in paracardiac region
Figure 3
Figure 3
CT scan chest showing bronchiectatic changes and consolidation at lower lobes (more on right side)
See this image and copyright information in PMC

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