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Review
. 2010 Sep;4(3):246-8.
doi: 10.1007/s12105-010-0185-3. Epub 2010 Jun 9.

Intranasal eosinophilic angiocentric fibrosis: a case report and review

Jumin Sunde  1 , Kathrina A Alexander, Vishnu V B Reddy, Bradford A Woodworth
Affiliations
Review

Intranasal eosinophilic angiocentric fibrosis: a case report and review

Jumin Sunde et al. Head Neck Pathol. 2010 Sep.

Abstract

Eosinophilc angiocentric fibrosis is a rare fibrosing vasculitis of unknown etiology that is progressive and potentially disfiguring. It has a predilection for the upper airways presenting most commonly as an obstructing mass lesion that is diagnosed histologically. Thus far, it has been nonfatal in the more than 40 reported cases; however, subglottic and ocular involvement has resulted in significant morbidity in several patients. Treatment has been challenging with persistent disease in most cases. The current case is a prototypical presentation with a limited nasal septal lesion providing the opportunity to discuss clinically relevant issues and increase awareness.

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Figures

Fig. 1
Fig. 1
Sinus CT shows 2.8 × 1.7 cm soft tissue density mass
Fig. 2
Fig. 2
Low power view (20× objective)
Fig. 3
Fig. 3
High power view (40× objective)
See this image and copyright information in PMC

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