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Comment
. 2010 Jun 15;107(24):10773-4.
doi: 10.1073/pnas.1005135107. Epub 2010 Jun 8.

Neuronal correlate of BOLD signal fluctuations at rest: err on the side of the baseline

Fahmeed Hyder  1 , Douglas L Rothman
Affiliations
Comment

Neuronal correlate of BOLD signal fluctuations at rest: err on the side of the baseline

Fahmeed Hyder et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Schema of neuronal histogram and neuronal energetics. Histograms of total neuronal activity represented by distribution of firing rates (ν) of the same neuronal ensemble, composed of many neurons, in low (blue; left) and high (green; right) baseline energy states. The histograms can be converted to CMRO2 by multiplying the number of neurons firing at a given rate over the entire range of frequencies. See refs. 5 and for details on neuronal histogram and neuronal energetics.
See this image and copyright information in PMC

Comment on

  • Neural basis of global resting-state fMRI activity.
    Schölvinck ML, Maier A, Ye FQ, Duyn JH, Leopold DA. Schölvinck ML, et al. Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10238-43. doi: 10.1073/pnas.0913110107. Epub 2010 May 3. Proc Natl Acad Sci U S A. 2010. PMID: 20439733 Free PMC article.

References

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    1. Shulman RG, Rothman DL. Interpreting functional imaging studies in terms of neurotransmitter cycling. Proc Natl Acad Sci USA. 1998;95:11993–11998. - PMC - PubMed
    1. Arieli A, Sterkin A, Grinvald A, Aertsen A. Dynamics of ongoing activity: Explanation of the large variability in evoked cortical responses. Science. 1996;273:1868–1871. - PubMed
    1. Smith AJ, et al. Cerebral energetics and spiking frequency: The neurophysiological basis of fMRI. Proc Natl Acad Sci USA. 2002;99:10765–10770. - PMC - PubMed

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