Effects of vibrissectomy during early postnatal ontogenesis in rat pups on behavioral development

Abstract

The effects of daily trimming of the whiskers in rat pups from day 2 or day 9 to day 20 on eye opening time and the formation of early behavioral reactions, i.e., walking, rearing, grooming, and manipulatory activity, were studied in rat pups subjected to deprivation and siblings reared with them. Rat pups subjected to vibrissectomy from day 2 of life and their siblings showed acceleration of eye opening, maturation of grooming, and rearing without support; the formation of manipulatory activity was delayed, as were changes in the structures of correlational relationships between the times at which behavioral reactions formed and eye opening occurred. Vibrissectomy from day 9 of life eliminated most correlational relationships in deprived animals without impairing the dynamics of the development of early behavioral reactions. Siblings showed delayed formation of manipulatory activity, though changes in the structure of correlational relationships were less significant than in deprived animals.