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Review
. 1991 Jul;54(1 Suppl):188S-192S.
doi: 10.1093/ajcn/54.1.188S.

Application of intermediate biomarkers to studies of cancer prevention in the gastrointestinal tract: introduction and perspective

M Lipkin  1
Affiliations
Review

Application of intermediate biomarkers to studies of cancer prevention in the gastrointestinal tract: introduction and perspective

M Lipkin. Am J Clin Nutr. 1991 Jul.

Abstract

In this article, abnormalities in the proliferation and differentiation of gastrointestinal cells are described in diseases that increase predisposition to gastrointestinal cancer. Recent findings related to the effects of calcium on gastrointestinal cell proliferation, differentiation, and tumor occurrence in rodent models and in human subjects are summarized.

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