Anticancer drugs: A double strike at kinases

Comment

Charlotte Harrison. Nat Rev Drug Discov. 2010 Apr.

. 2010 Apr;9(4):270.

doi: 10.1038/nrd3152.

No abstract available

Comment on

Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF.
Murphy EA, Shields DJ, Stoletov K, Dneprovskaia E, McElroy M, Greenberg JI, Lindquist J, Acevedo LM, Anand S, Majeti BK, Tsigelny I, Saldanha A, Walsh B, Hoffman RM, Bouvet M, Klemke RL, Vogt PK, Arnold L, Wrasidlo W, Cheresh DA. Murphy EA, et al. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4299-304. doi: 10.1073/pnas.0909299107. Epub 2010 Feb 12. Proc Natl Acad Sci U S A. 2010. PMID: 20154271 Free PMC article.

Computational Approaches Towards Kinases as Attractive Targets for Anticancer Drug Discovery and Development.
Hameed R, Khan A, Khan S, Perveen S. Hameed R, et al. Anticancer Agents Med Chem. 2019;19(5):592-598. doi: 10.2174/1871520618666181009163014. Anticancer Agents Med Chem. 2019. PMID: 30306880 Review.
Parkinsonian abnormality of foot strike: a phenomenon of ageing and/or one responsive to levodopa therapy?
Hughes JR, Bowes SG, Leeman AL, O'Neill CJ, Deshmukh AA, Nicholson PW, Dobbs SM, Dobbs RJ. Hughes JR, et al. Br J Clin Pharmacol. 1990 Feb;29(2):179-86. doi: 10.1111/j.1365-2125.1990.tb03617.x. Br J Clin Pharmacol. 1990. PMID: 2306409 Free PMC article. Clinical Trial.
Fans' Judgments About the 1994-95 Major League Baseball Players' Strike.
Mellor S, Paley MJ, Holzworth RJ. Mellor S, et al. Multivariate Behav Res. 1999 Jan 1;34(1):59-87. doi: 10.1207/s15327906mbr3401_3. Multivariate Behav Res. 1999. PMID: 26825129
A Forefoot Strike Requires the Highest Forces Applied to the Foot Among Foot Strike Patterns.
Hashizume S, Yanagiya T. Hashizume S, et al. Sports Med Int Open. 2017 Feb 21;1(2):E37-E42. doi: 10.1055/s-0042-122017. eCollection 2017 Feb. Sports Med Int Open. 2017. PMID: 30539084 Free PMC article.
New paradigms in anticancer therapy: targeting multiple signaling pathways with kinase inhibitors.
Faivre S, Djelloul S, Raymond E. Faivre S, et al. Semin Oncol. 2006 Aug;33(4):407-20. doi: 10.1053/j.seminoncol.2006.04.005. Semin Oncol. 2006. PMID: 16890796 Review.

Naringenin suppresses K562 human leukemia cell proliferation and ameliorates Adriamycin-induced oxidative damage in polymorphonuclear leukocytes.
Li RF, Feng YQ, Chen JH, Ge LT, Xiao SY, Zuo XL. Li RF, et al. Exp Ther Med. 2015 Mar;9(3):697-706. doi: 10.3892/etm.2015.2185. Epub 2015 Jan 16. Exp Ther Med. 2015. PMID: 25667616 Free PMC article.