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. 2010 Jul;67(3):291-3.
doi: 10.1016/j.diagmicrobio.2010.02.009.

Rapid detection of vancomycin-resistant enterococci from rectal swabs by the Cepheid Xpert vanA/vanB assay

Nancy Bourdon  1 , Raphaël Bérenger, Romain Lepoultier, Audrey Mouet, Claire Lesteven, France Borgey, Marguerite Fines-Guyon, Roland Leclercq, Vincent Cattoir
Affiliations

Rapid detection of vancomycin-resistant enterococci from rectal swabs by the Cepheid Xpert vanA/vanB assay

Nancy Bourdon et al. Diagn Microbiol Infect Dis. 2010 Jul.

Abstract

The detection of vancomycin-resistant enterococci using a novel commercial multiplex real-time polymerase chain reaction assay (Xpert vanA/vanB, Cepheid, Sunnyvale, CA) was evaluated on 804 rectal swab specimens. Compared to enriched culture, sensitivity and negative predictive value of this method were 100%. Many false-positive results were recovered (sensitivity, 85.4%; positive predictive value, 8.7%), especially for the vanB gene.

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