Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Apr;90(2):321-3.
doi: 10.1016/j.rvsc.2010.05.024. Epub 2010 Jun 12.

Proinflammatory cytokine expression in the lung of pigs with porcine circovirus type 2-associated respiratory disease

Joon-Seok Chae  1 , Kyoung-Seong Choi
Affiliations

Proinflammatory cytokine expression in the lung of pigs with porcine circovirus type 2-associated respiratory disease

Joon-Seok Chae et al. Res Vet Sci. 2011 Apr.

Abstract

Porcine circovirus type 2 (PCV2) causes a significant health problem for the swine industry worldwide. In this study, we investigated the cytokine expression profiles (IFN-γ, IL-1α, IL-8, and IL-10) in the lungs of pigs with PCV2-associated respiratory disease. The mRNA expressions of IL-1α and IL-8 were significantly up-regulated in pigs with PCV2-associated respiratory disease, while IL-10 expression was not detected. These results suggest that the increased expressions of proinflammatory cytokines in the lungs may play an important role in the immunopathologic response in pigs with PCV2-associated respiratory disease.

PubMed Disclaimer

LinkOut - more resources