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. 1978 Apr 15;34(4):481-2.
doi: 10.1007/BF01935940.

Neuronal responses to extracellularly applied cyclic AMP:Role of the adenosine receptor

D A Taylor, T W Stone

Neuronal responses to extracellularly applied cyclic AMP:Role of the adenosine receptor

D A Taylor et al. Experientia. .

Abstract

At low doses, theophylline blocks the neuronal depressant effects of 5'-AMP, but not cyclic AMP. Higher doses (100 mg/kg) block cyclic AMP responses and reduce the effects of noradrenaline and GABA. It is concluded that cyclic AMP does not depress neurones via the adenosine receptor.

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References

    1. Mol Pharmacol. 1970 Jan;6(1):13-23 - PubMed
    1. Can J Physiol Pharmacol. 1974 Dec;52(6):1226-9 - PubMed
    1. Brain Res. 1974 May 31;72(1):79-97 - PubMed
    1. Rev Physiol Biochem Pharmacol. 1975;74:1-103 - PubMed
    1. Pharmacol Res Commun. 1976 Feb;8(1):65-79 - PubMed