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. 2010 Jul 28;46(28):5169-71.
doi: 10.1039/c002748k. Epub 2010 Jun 11.

Photochemically driven intercalation of small molecules into DNA by in situ irradiation

Maria Letizia Di Pietro  1 , Fausto Puntoriero, Fabien Tuyéras, Philippe Ochsenbein, Philippe P Lainé, Sebastiano Campagna
Affiliations

Photochemically driven intercalation of small molecules into DNA by in situ irradiation

Maria Letizia Di Pietro et al. Chem Commun (Camb). .

Abstract

Intercalation of small molecules into DNA is photochemically achieved by in situ irradiation of a tetraaryl-pyridinium species. Such a "DNA intercalation on demand" process could highlight an alternative pathway to anticancer basic research, based on photo-activable DNA binders.

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