Functional genomics: One gene or two?

Comment

Tanita Casci. Nat Rev Genet. 2010 Jul.

. 2010 Jul;11(7):453.

doi: 10.1038/nrg2816.

No abstract available

Comment on

Ohnologs in the human genome are dosage balanced and frequently associated with disease.
Makino T, McLysaght A. Makino T, et al. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9270-4. doi: 10.1073/pnas.0914697107. Epub 2010 May 3. Proc Natl Acad Sci U S A. 2010. PMID: 20439718 Free PMC article.
A general lack of compensation for gene dosage in yeast.
Springer M, Weissman JS, Kirschner MW. Springer M, et al. Mol Syst Biol. 2010 May 11;6:368. doi: 10.1038/msb.2010.19. Mol Syst Biol. 2010. PMID: 20461075 Free PMC article.
The relationship among gene expression, the evolution of gene dosage, and the rate of protein evolution.
Gout JF, Kahn D, Duret L; Paramecium Post-Genomics Consortium. Gout JF, et al. PLoS Genet. 2010 May 13;6(5):e1000944. doi: 10.1371/journal.pgen.1000944. PLoS Genet. 2010. PMID: 20485561 Free PMC article.