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Case Reports
. 2010 May;22(2):191-3.
doi: 10.5021/ad.2010.22.2.191. Epub 2010 May 18.

A case of eccrine spiradenoma in a patient with neurofibromatosis

Jong Wook Park  1 , Sun Namkoong, Jimin Chung, Kyung Eun Jung, Sang A Oh, Yong Woo Cinn, Myung Hwa Kim
Affiliations
Case Reports

A case of eccrine spiradenoma in a patient with neurofibromatosis

Jong Wook Park et al. Ann Dermatol. 2010 May.

Abstract

Neurofibromatosis is a systemic hereditary disorder with varied manifestations in bone, soft tissue, the nervous system and skin. Cutaneous manifestations of neurofibromatosis are characterized by café-au-lait macules, multiple neurofibromas, Lisch nodules and intertriginous freckling. Some benign or malignant tumors such as juvenile xanthogranuloma, pheochromocytoma, and malignant melanoma can accompany neurofibromatosis. But, in the English literature, no case of eccrine spiradenoma associated with neurofibromatosis has been reported. Eccrine spiradenoma is a benign uncommon neoplasm of skin adnexa. It presents as a painful, slow-growing and solitary nodule on the head or upper trunk. Here, we report a rare case of eccrine spiradenoma in a patient with neurofibromatosis.

Keywords: Eccrine spiradenoma; Neurofibromatosis.

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Figures

Fig. 1
Fig. 1
(A) Flesh-colored subcutaneous tumor of lower back. (B) Several café-au-lait macules and diffuse freckles on trunk.
Fig. 2
Fig. 2
(A) Well-defined dermal nest of basaloid cells without connections to the epidermis (H&E, ×12.5). (B) Two types of epithelial cells arranged in intertwining cords with small lumina (H&E, ×400).
See this image and copyright information in PMC

References

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