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Case Reports
. 2010 May;22(2):216-8.
doi: 10.5021/ad.2010.22.2.216. Epub 2010 May 18.

A Case of Hand-foot-mouth Disease in an Immunocompetent Adult

Jung U Shin  1 , Sang Ho Oh, Ju Hee Lee
Affiliations
Case Reports

A Case of Hand-foot-mouth Disease in an Immunocompetent Adult

Jung U Shin et al. Ann Dermatol. 2010 May.

Abstract

Hand-foot-mouth (HFM) disease is primarily a disease of children, although it can be seen in immunocompromised adults. We describe a case of HFM disease in a 35-year-old immunocompetent male. He presented with multiple, 1~2 mm sized, erythematous vesicular papules on both hands and feet. Histopathological findings of a skin biopsy showed superficial perivascular lymphocytic infiltration, focal keratinocyte necrosis, and reticular degeneration. Because delayed diagnosis can cause spread of the disease to children, dermatologists should be aware that HFM disease can occur in adults with intact immune systems.

Keywords: Hand-foot-mouth disease; Immunocompetent adult.

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Figures

Fig. 1
Fig. 1
(A) Multiple erythematous papules and vesicles are seen on the fourth finger of the left hand. (B) Multiple erythematous papules and vesicles on the dorsum of the feet.
Fig. 2
Fig. 2
Superficial perivenular and junctional lymphocytic infiltration, epidermal necrosis associated with foci of necrotic keratinocytes, and reticular degeneration of epidermal cells (H&E, ×100).
See this image and copyright information in PMC

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