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Comment
. 2010 Jun 11;141(6):920-2.
doi: 10.1016/j.cell.2010.05.038.

A twist on potassium channel gating

Wei Zhou  1 , Lily Jan
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A twist on potassium channel gating

Wei Zhou et al. Cell. .
Free article

Abstract

The selectivity filter of potassium channels, the narrowest segment of the pore, permits only potassium ions to diffuse through the pore. Clarke et al. (2010) now present 11 structures of an inwardly rectifying potassium channel, providing evidence that the selectivity filter functions in channel gating and conformational changes in the cytoplasmic domains correlate with pore opening.

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