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Comparative Study
. 2008 Sep;1(3):232-5.
doi: 10.1007/s12265-008-9026-0. Epub 2008 May 10.

Engineered heart tissue: high throughput platform for dissection of complex diseases

Jozef Lazar  1 , Howard J Jacob, Tetsuro Wakatsuki
Affiliations
Comparative Study

Engineered heart tissue: high throughput platform for dissection of complex diseases

Jozef Lazar et al. J Cardiovasc Transl Res. 2008 Sep.

Abstract

The polygenic nature of resistance/sensitivity of the heart to ischemia is generally accepted. Unfortunately, little is known about gene(s) involved in response to this insult. The goal of present study is to introduce new tool, engineered heart tissue (EHT), for accelerating positional cloning and for providing novel functional assays.

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