Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2010 Oct;49(10):1806-14.
doi: 10.1093/rheumatology/keq167. Epub 2010 Jun 18.

Takayasu arteritis in children and adolescents

Juergen Brunner  1 , Brian M Feldman, Pascal N Tyrrell, Jasmin B Kuemmerle-Deschner, Lothar B Zimmerhackl, Ingmar Gassner, Susanne M Benseler
Affiliations
Review

Takayasu arteritis in children and adolescents

Juergen Brunner et al. Rheumatology (Oxford). 2010 Oct.

Abstract

Takayasu arteritis is a devastating vasculitis of the aorta and its major branches. The clinical manifestations in paediatric patients are less specific than in adults: in children the disease presents with fever, arthralgias and hypertension. Intramural inflammation results in narrowing of the blood vessel lumen and therefore hypoperfusion of the parenchyma. Conventional angiography is the gold standard diagnostic procedure. Corticosteroids, cyclophosphamide, MTX and biological therapies such as TNF-α blocking agents are treatment options.

PubMed Disclaimer