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. 2010 Jun 21:5:22.
doi: 10.1186/1749-8546-5-22.

Pharmacological effects of Salvia miltiorrhiza (Danshen) on cerebral infarction

Tsai-Hui Lin  1 , Ching-Liang Hsieh
Affiliations

Pharmacological effects of Salvia miltiorrhiza (Danshen) on cerebral infarction

Tsai-Hui Lin et al. Chin Med. .

Abstract

Danshen, the dried root of Salvia miltiorrhiza, is a Chinese medicine used to promote blood flow and treat vascular disease. The present article reviews the pharmacological effects of Danshen on cerebral infarction and possible interactions between Danshen and Western drugs. Danshen may reduce or prolong the development of atherosclerosis and may have anti-hypertensive and anti-platelet aggregation effects, which prevent cerebral infarction. Danshen may enhance endogenous anti-oxidative enzyme activities such as the expression of endothelial nitric oxide synthase and may scavenge oxygen free radicals. Prevention and treatment of cerebral infarction by Danshen involves multiple pathways, including anti-atherosclerosis, anti-hypertension, anti-platelet aggregation, anti-inflammatory and anti-oxidative effects.

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References

    1. Dietl M, Pohle R, Weingärtner M, Polgar R, Grässel E, Schwab S, Kolominsky-Rabas P. Stroke etiology and long-term need of care in ischemic stroke patients. Fortschr Neurol Psychiatr. 2009;77(12):714–719. doi: 10.1055/s-0028-1109912. - DOI - PubMed
    1. Albers GW, Amarenco P, Easton JD, Sacco RL, Teal P. Chest. 8. 6. Vol. 133. 2008. Antithrombotic and thrombolytic therapy for ischemic stroke: American college of chest physicians evidence-based clinical practice guidelines; pp. 630S–669S. - DOI - PubMed
    1. Mostaza JM, Martín-Jadraque R, Vicente I, San Martin MA, Lahoz C. Patients at high risk of cerebrovascular disease: the REACH study. Cerebrovasc Dis. 2009;27(1):77–81. doi: 10.1159/000200443. - DOI - PubMed
    1. Liu LS, Caguioa ES, Park CG, Quek DKL, Saito I, Venketasubramanian N, Wong KSL, Reid JL. Reducing stroke risk in hypertensive patients: Asian Consensus Conference recommendations. Int J Stroke. 2006;1(3):150–157. doi: 10.1111/j.1747-4949.2006.00041.x. - DOI - PubMed
    1. Tuttolomondo A, Di Sciacca R, Di Raimondo D, Arnao V, Renda C, Pinto A, Licata G. Neuron protection as a therapeutic target in acute ischemic stroke. Curr Top Med Chem. 2009;9(14):1317–1334. doi: 10.2174/156802609789869646. - DOI - PubMed

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