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. 2010 Mar;6(3):174-80.

Endoscopic and histologic findings in pediatric inflammatory bowel disease

Gareth P Jevon  1 , Ravikumara Madhur
Affiliations

Endoscopic and histologic findings in pediatric inflammatory bowel disease

Gareth P Jevon et al. Gastroenterol Hepatol (N Y). 2010 Mar.

Abstract

Inflammatory bowel disease (IBD) is an increasingly important cause of gastrointestinal pathology in children. Approximately 25% of IBDs present before the patient is 20 years of age. Accurate diagnosis and differentiation between Crohn's disease (CD) and ulcerative colitis (UC) is important in planning treatment strategies, particularly in children. Endoscopy, which allows direct visualization of gastrointestinal mucosa and biopsy of multiple sites, is an integral part of this diagnostic process. Although no endoscopic lesion is pathognomonic of IBD, certain features are highly suggestive of either CD or UC. In this article, we review and attempt to correlate endoscopic and histologic findings in IBD that have particular emphasis on the pediatric population.

Keywords: Crohn's disease; Inflammatory bowel disease; children; pathology; ulcerative colitis.

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Figures

Figure 1
Figure 1
Aphthous ulcers in early colonic Crohn's disease.
Figure 2
Figure 2
Deep serpigous ulcers in established Crohn's disease.
Figure 3
Figure 3
Ulcerative colitis showing diffuse erythema and contiguous superficial ulcerations.
Figure 4
Figure 4
A well-defined Crohn's disease granuloma in the antrum.
Figure 5
Figure 5
Focal antral inflammation in Crohn's disease.
See this image and copyright information in PMC

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