Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Apr;6(4):246-54.

Risk factors for pancreatic adenocarcinoma and prospects for screening

G Anton Decker, Mashal J Batheja, Joseph M Collins, Alvin C Silva, Kristin L Mekeel, Adyr A Moss, Cuong C Nguyen, Douglas F Lake, Laurence J Miller

Risk factors for pancreatic adenocarcinoma and prospects for screening

G Anton Decker et al. Gastroenterol Hepatol (N Y). 2010 Apr.

Abstract

Pancreatic cancer has one of the worst survival rates of any cancer and is the fourth leading cause of cancer mortality. Early detection and surgery are the patient's best chance for cure. However, symptoms are typically vague and occur when the cancer is unresectable. Population-based mass screening is not practical for this rare disease, though screening and early detection in asymptomatic high-risk patient populations may be indicated.

Keywords: Pancreatic cancer; inherited risk factors; noninherited risk factors; screening.

PubMed Disclaimer

References

    1. Jemal A, Siegel R, Ward E, Murray T, Xu J, et al. Cancer statistics, 2006. CA Cancer J Clin. 2006;56:106–130. - PubMed
    1. Neoptolemos JP, Stocken DD, Friess H, Bassi C, Dunn JA, et al. A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med. 2004;350:1200–1210. - PubMed
    1. Li D, Xie K, Wolff R, Abbruzzese JL. Pancreatic cancer. Lancet. 2004;363:1049–1057. - PubMed
    1. Nakao A, Harada A, Nonami T, Kaneko T, Takagi H. Clinical significance of carcinoma invasion of the extrapancreatic nerve plexus in pancreatic cancer. Pancreas. 1996;12:357–361. - PubMed
    1. Yeo CJ, Cameron JL, Lillemoe KD, Sitzmann JV, Hruban RH, et al. Pancreaticoduodenectomy for cancer of the head of the pancreas. 201 patients. Ann Surg. 1995;221:721–731. discussion 731-733. - PMC - PubMed

LinkOut - more resources