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. 2009 May;23(2):141-7.
doi: 10.1055/s-0029-1214166.

Adjunctive therapies in the treatment of osteomyelitis

Robert C Fang  1 , Robert D Galiano
Affiliations

Adjunctive therapies in the treatment of osteomyelitis

Robert C Fang et al. Semin Plast Surg. 2009 May.

Abstract

The current management for chronic osteomyelitis centers on adequate antibiotic coverage and surgical debridement of nonviable tissue. The eradication of osteomyelitis, however, often involves a prolonged and frustrating course of management. Nonsurgical adjunctive modalities have not been widely used, mostly due to a lack of perceived efficacy, and have remained in a state of infancy. In this article, we will outline the rationale, current status, and evidence for several potential adjuncts to osteomyelitis management.

Keywords: Osteomyelitis; adjunctive therapy; biofilm; growth factor; hyperbaric oxygen therapy.

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References

    1. Lew D P, Waldvogel F A. Osteomyelitis. Lancet. 2004;364:369–379. - PubMed
    1. Parsons B, Strauss E. Surgical management of chronic osteomyelitis. Am J Surg. 2004;188(Suppl):57–66. - PubMed
    1. Tice A D, Hoaglund P A, Shoultz D A. Outcomes of osteomyelitis among patients treated with outpatient parenteral antimicrobial therapy. Am J Med. 2003;114:723–728. - PubMed
    1. Lipsky B A, Berendt A R, Deery H G, et al. Diagnosis and treatment of diabetic foot infections. Plast Reconstr Surg. 2006;117(7, Suppl):212S–238S. - PubMed
    1. Lavery L A, Armstrong D G, Wunderlich R P, Mohler M J, Wendel C S, Lipsky B A. Risk factors for foot infections in individuals with diabetes. Diabetes Care. 2006;29:1288–1293. - PubMed