[Chondromyxoid fibroma of the nasal septum]

Abstract

Introduction: Chondromyxoid fibroma (CMF) is a rare benign tumor, typically occurring in the metaphysis of long bones. Involvement of craniofacial bones is extremely unusual. The histologic diagnosis of this tumor is difficult because of its similarities to chondrosarcoma. Preferably, chondromyxoid fibroma is treated by complete local excision. Recurrences, or soft tissue implants, may follow incomplete curettage.

Aim of study: Presentation of the case of 51-year-old woman who presented with a CFM of the nasal septum with extension into the maxillary and sphenoid sinuses. In addition, a literature review of the clinical and histologic features, as well as recommended modalities of treatment, are presented.

Material and methods: Analysis of clinical records of patient treated of CMF in Department of Otolaryngology Warsaw Medical Univercity. Radiologic imaging showed a soft tissue lesion invading the adjacent bony structures. The initial microscopic examination of a segment of the tumor gives no diagnose. The tumor was excised. Postoperative microscopical examination of the tumor revealed the typical pathologic features of CMF. Patient was free of disease at 12-month follow-up. After it signs of recurrence appeared. Reoperation was performed.

Conclusion: Although surgery is a base of treatment, radiotherapy should also be discussed. Surgical excision must be complete. Radiotherapy should to be reserved for the cases that are surgically difficult to reach. Because of the similarities between CMF and chondrosarcoma, great care must be taken in the assessment of the biopsy.