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. 1978 Mar 15;56(6):309-10.
doi: 10.1007/BF01489178.

Perhexiline induces generalized lipidosis in rats

H Lüllmann, R Lüllmann-Rauch

Perhexiline induces generalized lipidosis in rats

H Lüllmann et al. Klin Wochenschr. .

Abstract

Administration of perhexiline (Pexide) to rats causes generalized occurrence of lamellated and crystalloid cytoplasmic inclusions which resemble those described in patients with perhexiline-induced polyneuropathy. It is concluded that perhexiline being an amphiphilic cationic compound is a potent inducer of generalized lipidosis.

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