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. 2010 Dec;20(12):2882-9.
doi: 10.1007/s00330-010-1866-8. Epub 2010 Jun 23.

Pulmonary ventilation and perfusion imaging with dual-energy CT

Sven F Thieme  1 , Sandra Hoegl, Konstantin Nikolaou, Juergen Fisahn, Michael Irlbeck, Daniel Maxien, Maximilian F Reiser, Christoph R Becker, Thorsten R C Johnson
Affiliations

Pulmonary ventilation and perfusion imaging with dual-energy CT

Sven F Thieme et al. Eur Radiol. 2010 Dec.

Abstract

Objective: To evaluate the feasibility of dual-energy CT (DECT) ventilation imaging in combination with DE perfusion mapping for a comprehensive assessment of ventilation, perfusion, morphology and structure of the pulmonary parenchyma.

Methods: Two dual-energy CT acquisitions for xenon-enhanced ventilation and iodine-enhanced perfusion mapping were performed in patients under artificial respiration. Parenchymal xenon and iodine distribution were mapped and correlated with structural or vascular abnormalities.

Results: In all datasets, image quality was sufficient for a comprehensive image reading of the pulmonary CTA images, lung window images and pulmonary functional parameter maps and led to expedient results in each patient.

Conclusion: With dual-source CT systems, DECT of the lung with iodine or xenon administration is technically feasible and makes it possible to depict the regional iodine or xenon distribution representing the local perfusion and ventilation.

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