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Case Reports
. 2010 Sep;92(6):W5-8.
doi: 10.1308/147870810X12699662980952. Epub 2010 Jun 23.

Neuroendocrine carcinoma arising within a retroperitoneal mature teratoma

Alice L Scott  1 , Nima Abbassi-Ghadi, Charles M G Archer, Rajiv Swamy, Sanjay Gupta
Affiliations
Case Reports

Neuroendocrine carcinoma arising within a retroperitoneal mature teratoma

Alice L Scott et al. Ann R Coll Surg Engl. 2010 Sep.

Abstract

We discuss an unusual case of a large cystic mass arising in the left upper quadrant of a 48-year-old woman. Radiological investigations could not confirm the origin or the nature of the mass. A laparatomy revealed a large retroperitoneal cystic mass sandwiched between the left adrenal, spleen and the gastro-oesophageal junction. Histological analysis confirmed a mature teratoma of the retroperitoneum with neuroendocrine carcinoma arising within it. To our knowledge this is only the second reported case of its kind.

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Figures

Figure 1
Figure 1
Transverse CT image of abdomen at level of T12 vertebrae. Note the large tumour mass (T) filling the left hemi-abdomen and displacing the stomach (S) superiorly.
Figure 2
Figure 2
Transverse CT image of mature teratoma (T) at level of L2 vertebrae. Note the spleen (Sp) and left kidney (LK) which have been displaced inferiorly.
Figure 3
Figure 3
Laparotomy with retroperitoneal teratoma (T) partly mobilised and adherent to the gastro-oesophageal junction (GOJ).
Figure 4
Figure 4
Mature teratoma – cyst wall incised and internal surface displayed.
Figure 5
Figure 5
Solid nodule component of cyst wall which displays neuroendocrine morphology (×5, H&E).
Figure 6
Figure 6
Solid neuroendocrine carcinoma with atypical mitotic figures (arrows; x20, H&E).
See this image and copyright information in PMC

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