An unusual cause of fever in a neonate: influenza A (H1N1) virus pneumonia
- PMID: 20575093
- DOI: 10.1002/ppul.21245
An unusual cause of fever in a neonate: influenza A (H1N1) virus pneumonia
Abstract
The 2009 flu outbreak in humans, known as H1N1 influenza A, refers to influenza A due to a new H1N1 strain called swine-origin influenza virus A. The signs and symptoms of novel influenza A (H1N1) virus infection are similar to those of seasonal influenza, and specific diagnostic testing is required to distinguish novel influenza A (H1N1) virus from seasonal influenza virus. It results in various degrees of infection, ranging from mild to severe to fatal. For the treatment of swine-origin influenza virus A oseltamivir and zanamivir are effective in most cases. Influenza A (H1N1) pneumonia in the newborn has not been yet reported in the literature. To our knowledge, this is the first report of a neonate of pneumonia in which influenza A (H1N1) virus was isolated.
Comment in
-
Influenza a (H1N1) virus pneumonia in newborns: experience of a referral level III neonatal intensive care unit in Turkey.Pediatr Pulmonol. 2011 Feb;46(2):201-2; author reply 203. doi: 10.1002/ppul.21343. Epub 2010 Oct 20. Pediatr Pulmonol. 2011. PMID: 20963837 No abstract available.
-
Novel H1N1 influenza pneumonia in neonate.Pediatr Pulmonol. 2011 Apr;46(4):412; author reply 413. doi: 10.1002/ppul.21382. Epub 2010 Dec 30. Pediatr Pulmonol. 2011. PMID: 21438173 No abstract available.
Similar articles
-
Clinical effectiveness of oseltamivir and zanamivir for treatment of influenza A virus subtype H1N1 with the H274Y mutation: a Japanese, multicenter study of the 2007-2008 and 2008-2009 influenza seasons.Clin Infect Dis. 2009 Dec 15;49(12):1828-35. doi: 10.1086/648424. Clin Infect Dis. 2009. PMID: 19911968
-
Reduced effectiveness of oseltamivir in children infected with oseltamivir-resistant influenza A (H1N1) viruses with His275Tyr mutation.Pediatr Infect Dis J. 2010 Oct;29(10):898-904. doi: 10.1097/INF.0b013e3181de9d24. Pediatr Infect Dis J. 2010. PMID: 20442686
-
Failure of zanamivir therapy for pneumonia in a bone-marrow transplant recipient infected by a zanamivir-sensitive influenza A (H1N1) virus.Antivir Ther. 2007;12(4):571-6. Antivir Ther. 2007. PMID: 17668567
-
The use of antiviral agents for the management of severe influenza.Crit Care Med. 2010 Apr;38(4 Suppl):e43-51. doi: 10.1097/CCM.0b013e3181c85229. Crit Care Med. 2010. PMID: 19935416 Review.
-
Influenza vaccination, diagnosis, and treatment in children.Pediatr Emerg Care. 2011 Aug;27(8):760-9; quiz 770-1. doi: 10.1097/PEC.0b013e31822843f2. Pediatr Emerg Care. 2011. PMID: 21822091 Review.
Cited by
-
Oseltamivir pharmacokinetics and clinical experience in neonates and infants during an outbreak of H1N1 influenza A virus infection in a neonatal intensive care unit.Antimicrob Agents Chemother. 2012 Jul;56(7):3833-40. doi: 10.1128/AAC.00290-12. Epub 2012 May 7. Antimicrob Agents Chemother. 2012. PMID: 22564835 Free PMC article. Clinical Trial.
-
Pandemic (H1N1) 2009 in neonates, Japan.Emerg Infect Dis. 2011 Sep;17(9):1763-5. doi: 10.3201/eid1709.101803. Emerg Infect Dis. 2011. PMID: 21888818 Free PMC article. No abstract available.
-
Clinical analysis of influenza in the neonatal intensive care unit.Ital J Pediatr. 2024 Sep 18;50(1):184. doi: 10.1186/s13052-024-01742-6. Ital J Pediatr. 2024. PMID: 39294774 Free PMC article.
-
Influenza A (H1N1) and Respiratory Syncytial Virus (RSV) Coinfection in a Newborn Child: A Case Report.Adv Exp Med Biol. 2021;1324:29-34. doi: 10.1007/5584_2020_602. Adv Exp Med Biol. 2021. PMID: 33346902
-
Oseltamivir pharmacokinetics, dosing, and resistance among children aged <2 years with influenza.J Infect Dis. 2013 Mar 1;207(5):709-20. doi: 10.1093/infdis/jis765. Epub 2012 Dec 10. J Infect Dis. 2013. PMID: 23230059 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical