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Randomized Controlled Trial
. 2010 Dec;94(7):2902-4.
doi: 10.1016/j.fertnstert.2010.04.077. Epub 2010 Jun 26.

Higher birth rate after recombinant hCG triggering compared with urinary-derived hCG in single-blastocyst IVF antagonist cycles: a randomized controlled trial

Evangelos G Papanikolaou  1 , Human Fatemi, Michel Camus, Dimitra Kyrou, Nikos P Polyzos, Peter Humaidan, Basil Tarlatzis, Paul Devroey, Herman Tournaye
Affiliations
Randomized Controlled Trial

Higher birth rate after recombinant hCG triggering compared with urinary-derived hCG in single-blastocyst IVF antagonist cycles: a randomized controlled trial

Evangelos G Papanikolaou et al. Fertil Steril. 2010 Dec.

Abstract

In a prospective randomized controlled trial, 119 patients were randomized to receive either recombinant hCG (250 μg) or urinary-derived hCG (10,000 IU) for final oocyte maturation in an antagonist protocol with a fixed dose of recombinant FSH (187.5 IU) and predefined single blastocyst transfer. The delivery rate was improved in the recombinant hCG group compared with the urinary-derived hCG group (44.1 vs. 25.7, respectively); however, adequately powered randomized controlled trials are justified to ascertain whether this difference is true.

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