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Review
. 1991 Jul;29(4):324-30.
doi: 10.1016/0041-624x(91)90030-c.

Principles and recent developments in ultrasound contrast agents

N de Jong  1 , F J Ten Cate, C T Lancée, J R Roelandt, N Bom
Affiliations
Review

Principles and recent developments in ultrasound contrast agents

N de Jong et al. Ultrasonics. 1991 Jul.

Abstract

The behaviour of gas bubbles and gas encapsulated spheres as echographic contrast agents is reviewed. Compared with rigid spheres, gas bubbles are superior scattering agents and they offer a number of useful properties which can be exploited in a variety of ways. The analysis of their velocity of sound, back-scatter intensity, second harmonic emission and resonant frequency opens up new perspectives in the development of contrast agents for echocardiographic research with potential clinical applications.

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