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Case Reports
. 2010 Jul;68(1):111-4.
doi: 10.1002/ana.21996.

Acute necrotizing encephalopathy during novel influenza A (H1N1) virus infection

Paolo Mariotti  1 , Raffaele Iorio, Giovanni Frisullo, Domenico Plantone, Raffaella Colantonio, Tommaso Tartaglione, Anna Paola Batocchi, Piero Valentini
Affiliations
Case Reports

Acute necrotizing encephalopathy during novel influenza A (H1N1) virus infection

Paolo Mariotti et al. Ann Neurol. 2010 Jul.

Abstract

A novel swine-origin influenza A (H1N1) virus was recently identified in Mexico. Some cases of infection with neurological complications have been reported to date. We report a case of acute necrotizing encephalopathy associated with the novel H1N1 virus in a 2-year-old European girl who suddenly developed fever, seizures, and altered mental status. Brain and spinal cord magnetic resonance imaging showed bilateral symmetrical lesions of the insulae, thalami, geniculate bodies, and pons tegmentum suggestive of an acute necrotizing encephalopathy. An involvement of meninges and spinal cord was observed configuring an acute necrotizing meningoencephalomyelitis.

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  • A 2-year-old girl positive for 2009 AH1N1 pandemic influenza.
    Sandoval-Gutiérrez JL, Arcos M, Alva L, Volkow P, Ferrari T, Quiñones F, Vázquez-Pérez J, Ormsby CE, Hanssen F, Reséndiz A, Alcántara P, Pérez Padilla R, Bautista E. Sandoval-Gutiérrez JL, et al. Ann Neurol. 2011 Jan;69(1):217; author reply 217-8. doi: 10.1002/ana.22293. Ann Neurol. 2011. PMID: 21280099 No abstract available.

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