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. 2010 Aug;126(2):395-7.
doi: 10.1016/j.jaci.2010.05.008. Epub 2010 Jun 26.

Infants aged 12 months can mount adequate serotype-specific IgG responses to pneumococcal polysaccharide vaccine

Anne Balloch, Paul V Licciardi, Fiona M Russell, Edward K Mulholland, Mimi L K Tang

Infants aged 12 months can mount adequate serotype-specific IgG responses to pneumococcal polysaccharide vaccine

Anne Balloch et al. J Allergy Clin Immunol. 2010 Aug.

Abstract

This is the first study examining serotype-specific IgG responses following immunization with the polysaccharide vaccine Pneumovax® in infants aged 12 months in the absence of prior pneumococcal conjugate vaccine priming.

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Figures

Figure 1
Figure 1
Proportion of infants at one year of age (n=56) with an adequate serotype-specific IgG response 2-weeks following 23vPPV immunization. An adequate response is defined as a post-immunization titre ≥1.3μg/ml and/or a 4-fold increase over baseline titre. Grey bars represent ≥1.3μg/ml; white bars represent a 4-fold increase on baseline titre and black bars represent either ≥1.3μg/ml and/or a 4-fold increase on baseline titre.
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