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Comment
. 2010;14(3):170.
doi: 10.1186/cc9043. Epub 2010 Jun 23.

Red cell transfusion triggers in critically ill patients: time for some new TRICCs?

Timothy S Walsh  1
Affiliations
Comment

Red cell transfusion triggers in critically ill patients: time for some new TRICCs?

Timothy S Walsh. Crit Care. 2010.

Abstract

Current evidence suggests that critically ill patients tolerate anaemia well and that blood transfusions may increase the risk of adverse outcomes. Dr Sakr and colleagues present a contradictory analysis of a surgical ICU cohort, finding an association between blood transfusions and lower hospital mortality after adjustment for a range of potential confounders. Analyses of this kind are interesting and provocative, but are limited by residual confounding and bias by indication. The data emphasise the need for additional high quality trials of transfusion practice in critical care.

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References

    1. Sakr Y, Lobo S, Knuepfer S, Esser E, Bauer M, Settmacher U, Barz D, Reinhart K. Anemia and blood transfusion in a surgical intensive care unit. Crit Care. 2010;14:R92. doi: 10.1186/cc9026. - DOI - PMC - PubMed
    1. Marik PE, Corwin HL. Efficacy of red blood cell transfusion in the critically ill: a systematic review of the literature. Crit Care Med. 2008;36:2667–2674. doi: 10.1097/CCM.0b013e3181844677. - DOI - PubMed
    1. Hébert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, Tweeddale M, Schweitzer I, Yetisir E. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med. 1999;340:409–417. doi: 10.1056/NEJM199902113400601. - DOI - PubMed
    1. Carson JL, Reynolds RC, Klein HG. Bad bad blood? Crit Care Med. 2008;36:2707–2708. doi: 10.1097/CCM.0b013e3181843ee7. - DOI - PubMed
    1. Vincent JL, Sakr Y, Sprung C, Harboe S, Damas P. Are blood transfusions associated with greater mortality rates? Results of the Sepsis Occurrence in Acutely Ill Patients study. Anesthesiology. 2008;108:31–39. doi: 10.1097/01.anes.0000296070.75956.40. - DOI - PubMed

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