Dirty mouth? Should you clean it out? Decontamination for the prevention of pneumonia and mortality in the ICU
- PMID: 20587083
- PMCID: PMC2911748
- DOI: 10.1186/cc9048
Dirty mouth? Should you clean it out? Decontamination for the prevention of pneumonia and mortality in the ICU
Comment in
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Withholding selective decontamination of the digestive tract from critically ill patients must now surely be ethically questionable given the vast evidence base.Crit Care. 2010;14(5):443. doi: 10.1186/cc9255. Epub 2010 Oct 6. Crit Care. 2010. PMID: 21067554 Free PMC article. No abstract available.
Comment on
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Decontamination of the digestive tract and oropharynx in ICU patients.N Engl J Med. 2009 Jan 1;360(1):20-31. doi: 10.1056/NEJMoa0800394. N Engl J Med. 2009. PMID: 19118302 Clinical Trial.
References
Article details
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- Eric B Milbrandt, editor. Evidence-Based Medicine Journal Club. University of Pittsburgh Department of Critical Care Medicine;
References
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- de Smet AM, Kluytmans JA, Cooper BS, Mascini EM, Benus RF, van der Werf TS, van der Hoeven JG, Pickkers P, Bogaers-Hofman D, van der Meer NJ, Bernards AT, Kuijper EJ, Joore JC, Leverstein-van Hall MA, Bindels AJ, Jansz AR, Wesselink RM, de Jongh BM, Dennesen PJ, van Asselt GJ, te Velde LF, Frenay IH, Kaasjager K, Bosch FH, van Iterson M, Thijsen SF, Kluge GH, Pauw W, de Vries JW, Kaan JA, Arends JP, Aarts LP, Sturm PD, Harinck HI, Voss A, Uijtendaal EV, Blok HE, Thieme Groen ES, Pouw ME, Kalkman CJ, Bonten MJ. Decontamination of the digestive tract and oropharynx in ICU patients. N Engl J Med. 2009;360:20–31. doi: 10.1056/NEJMoa0800394. - DOI - PubMed
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- Chan EY, Ruest A, Meade MO, Cook DJ. Oral decontamination for prevention of pneumonia in mechanically ventilated adults: systematic review and meta-analysis. BMJ. 2007;334:889. doi: 10.1136/bmj.39136.528160.BE. - DOI - PMC - PubMed
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