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Case Reports
. 2010 Jul;16(7):1133-6.
doi: 10.3201/eid1607.091606.

Vaccine-associated paralytic poliomyelitis in immunodeficient children, Iran, 1995-2008

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Case Reports

Vaccine-associated paralytic poliomyelitis in immunodeficient children, Iran, 1995-2008

Shohreh Shahmahmoodi et al. Emerg Infect Dis. 2010 Jul.

Abstract

To determine the prevalence of vaccine-associated paralytic poliomyelitis (VAPP) in immunodeficient infants, we reviewed all documented cases caused by immunodeficiency-associated vaccine-derived polioviruses in Iran from 1995 through 2008. Changing to an inactivated polio vaccine vaccination schedule and introduction of screening of neonates for immunodeficiencies could reduce the risk for VAPP infection.

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