Review
doi: 10.1002/mas.20258.
Structural investigation of bacterial lipopolysaccharides by mass spectrometry and tandem mass spectrometry
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- PMID: 20589944
- DOI: 10.1002/mas.20258
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Review
Structural investigation of bacterial lipopolysaccharides by mass spectrometry and tandem mass spectrometry
Mass Spectrom Rev.
2010 Jul-Aug.
Abstract
Mass spectrometric studies are now playing a leading role in the elucidation of lipopolysaccharide (LPS) structures through the characterization of antigenic polysaccharides, core oligosaccharides and lipid A components including LPS genetic modifications. The conventional MS and MS/MS analyses together with CID fragmentation provide additional structural information complementary to the previous analytical experiments, and thus contribute to an integrated strategy for the simultaneous characterization and correct sequencing of the carbohydrate moiety.
2010 Wiley Periodicals, Inc.
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