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. 2010 Apr;74(2):118-23.

Distribution of genotypes of porcine reproductive and respiratory syndrome virus in Ontario during 2004-2007 and the association between genotype and clinical signs of disease

Thomas Rosendal  1 , Cate Dewey, Beth Young, Susy Carman, Li Ge, Zvonimir Poljak
Affiliations

Distribution of genotypes of porcine reproductive and respiratory syndrome virus in Ontario during 2004-2007 and the association between genotype and clinical signs of disease

Thomas Rosendal et al. Can J Vet Res. 2010 Apr.

Abstract
in English, French

Restriction fragment length polymorphism (RFLP) was first proposed to classify porcine reproductive and respiratory syndrome virus (PRRSV) in 1998. The primary objective of this study was to identify associations between different PRRSV RFLP types in swine herds in southern Ontario and clinical signs of disease in those herds. Herds included in the study submitted samples to the Animal Health Laboratory at the University of Guelph between September 2004 and August 2007. Each farm owner was surveyed to describe the clinical disease in the herd and the RFLP pattern of an isolate of PRRSV was obtained from a diagnostic sample. The most frequent isolates were RFLP types 1_4 (25.1%), 252 (14.7%), 134 (12%), and 1_2 (7.7%). The distribution of RFLP types in this study was found to be different from a previous investigation in Ontario. Those RFLP types most associated with clinical disease in the farrowing phase of production were 1_4, 1_2, and 134. The only virus type to be significantly associated with disease in the finisher phase was RFLP type 262. During the study period RFLP type 184 emerged in the population in November 2005.

En 1998 le polymorphisme de longueur des fragments de restriction (RFLP) a été proposé pour la première fois afin de classifier le virus du syndrome reproducteur et respiratoire porcin (PRRSV). L’objectif premier de la présente étude était d’identifier les associations entre les différents types de RFLP de PRRSV dans les troupeaux porcins dans le sud de l’Ontario et les signes cliniques de maladie dans ces troupeaux. Les troupeaux inclus dans l’étude ont soumis des échantillons au Animal Health Laboratory à l’University of Guelph durant la période de septembre 2004 à août 2007. Chaque propriétaire de ferme était questionné afin qu’il décrive les signes cliniques dans le troupeau et le profil RFLP d’un isolat de PRRSV était obtenu d’un échantillon diagnostique. Les isolats les plus fréquents avaient les types de RFLP 1_4 (25,1 %), 252 (14,7 %), 134 (12 %) et 1_2 (7,7 %). La distribution des types de RFLP dans cette étude était différente d’une enquête antérieure en Ontario. Dans cette dernière, les types de RFLP les plus fréquemment associés avec des signes cliniques dans la phase naisseur de cette production étaient 1_4, 1_2 et 134. Le seul type viral à être associé de manière significative avec la maladie dans la phase de finition était le type RFLP 262. Durant la période d’étude, le type RFLP 184 a émergé dans la population en novembre 2005.

(Traduit par Docteur Serge Messier)

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Figures

Figure 1
Figure 1
The temporal distribution of the ratio of the number of cases of the 3 most common types (1_4, 1_2, and 134) and RFLP type 184 over the total number of cases using a 60-day moving average.
See this image and copyright information in PMC

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