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. 2010 Aug 21;8(16):3627-30.
doi: 10.1039/c004344c. Epub 2010 Jun 30.

Design and synthesis of a highly selective fluorescent turn-on probe for thiol bioimaging in living cells

Xin Li  1 , Shijing Qian, Qiaojun He, Bo Yang, Jia Li, Yongzhou Hu
Affiliations

Design and synthesis of a highly selective fluorescent turn-on probe for thiol bioimaging in living cells

Xin Li et al. Org Biomol Chem. .

Abstract

A new fluorescent turn-on probe for the rapid optical sensing of thiols has been designed and synthesized. The probe displays high on/off signal ratios and high selectivity towards thiols. The potential of the probe as a biosensor for thiols was demonstrated by imaging of thiols in living cells.

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