Diagnosis and treatment of a patient with both psychotic and obsessive-compulsive symptoms
- PMID: 20595428
- PMCID: PMC3859191
- DOI: 10.1176/appi.ajp.2009.09070997
Diagnosis and treatment of a patient with both psychotic and obsessive-compulsive symptoms
Abstract
When a patient presents with both psychotic and obsessive-compulsive symptoms, the clinician is faced with a differential diagnosis that includes comorbid schizophrenia and obsessive-compulsive disorder (OCD), OCD with poor insight, and schizophrenia with antipsychotic-induced obsessive-compulsive symptoms. If the psychotic symptoms are subthresh-old or attenuated in form, the individual may have OCD and putative prodromal schizophrenia. The authors present a case to outline a strategy for differentiating among these possible diagnoses and for optimizing treatment.
Comment in
-
Schizophrenia and obsessive-compulsive disorder.Am J Psychiatry. 2010 Nov;167(11):1407-8. doi: 10.1176/appi.ajp.2010.10081111. Am J Psychiatry. 2010. PMID: 21041254 No abstract available.
Similar articles
-
[Obsessive-compulsive disorder and schizophrenia].Ryoikibetsu Shokogun Shirizu. 2003;(38):459-63. Ryoikibetsu Shokogun Shirizu. 2003. PMID: 12877026 Review. Japanese. No abstract available.
-
[Clozapine and obsessive-compulsive symptoms in schizophrenia. A case history of one patient].Nervenarzt. 1999 Jan;70(1):64-7. doi: 10.1007/s001150050401. Nervenarzt. 1999. PMID: 10087519 German.
-
Escitalopram in the treatment of patients with schizophrenia and obsessive-compulsive disorder: an open-label, prospective study.Int Clin Psychopharmacol. 2013 Mar;28(2):96-8. doi: 10.1097/YIC.0b013e32835bd24e. Int Clin Psychopharmacol. 2013. PMID: 23211492 Clinical Trial.
-
Obsessive-compulsive disorder and treatment with clozapine in 200 patients with recent-onset schizophrenia or related disorders.Eur Psychiatry. 2004 Dec;19(8):524. doi: 10.1016/j.eurpsy.2004.09.022. Eur Psychiatry. 2004. PMID: 15589719 No abstract available.
-
Obsessive-compulsive disorder in schizophrenia: clinical characteristics and treatment.CNS Drugs. 2004;18(14):989-1010. doi: 10.2165/00023210-200418140-00004. CNS Drugs. 2004. PMID: 15584769 Review.
Cited by
-
Cognitive-behavioural therapy for obsessive-compulsive disorder co-occurring with psychosis: Systematic review of evidence.World J Psychiatry. 2016 Dec 22;6(4):449-455. doi: 10.5498/wjp.v6.i4.449. eCollection 2016 Dec 22. World J Psychiatry. 2016. PMID: 28078209 Free PMC article.
-
Integration of Clozapine-associated Harm Obsessions into Cognitive Behavioral Conceptualization and Treatment Planning for Thought Broadcasting: A Case Study.J Psychiatr Pract. 2020 Jul;26(4):329-336. doi: 10.1097/PRA.0000000000000470. J Psychiatr Pract. 2020. PMID: 32692132 Free PMC article.
-
[Obsessive-compulsive symptoms in psychotic disorders: pathogenesis and treatment].Nervenarzt. 2022 Jul;93(7):688-694. doi: 10.1007/s00115-022-01332-z. Epub 2022 Jul 5. Nervenarzt. 2022. PMID: 35788721 Review. German.
-
Comorbid obsessive-compulsive symptoms in schizophrenia: contributions of pharmacological and genetic factors.Front Pharmacol. 2013 Aug 9;4:99. doi: 10.3389/fphar.2013.00099. eCollection 2013. Front Pharmacol. 2013. PMID: 23950745 Free PMC article.
-
Comorbid Obsessive-Compulsive Symptoms in Schizophrenia: Insight into Pathomechanisms Facilitates Treatment.Adv Med. 2014;2014:317980. doi: 10.1155/2014/317980. Epub 2014 Jun 11. Adv Med. 2014. PMID: 26556409 Free PMC article. Review.
References
-
- Reznik I, Yavin I, Stryjer R, Spivak B, Gonen N, Strous R, Mester R, Weizman A, Kotler M. Clozapine in the treatment of obsessive-compulsive symptoms in schizophrenia patients: a case series study. Pharmacopsychiatry. 2004;37:52–56. - PubMed
-
- Poyurovsky M, Glick I, Koran L. Lamotrigine augmentation in schizophrenia and schizoaffective patients with obsessive-compulsive symptoms. J Psychopharmacol. (Epub ahead of print, Dec 12, 2008) - PubMed
-
- Poyurovsky M, Weizman A, Weizman R. Obsessive-compulsive disorder in schizophrenia: clinical characteristics and treatment. CNS Drugs. 2004;18:989–1010. - PubMed
-
- Fenton WS, McGlashan TH. The prognostic significance of obsessive-compulsive symptoms in schizophrenia. Am J Psychiatry. 1986;143:437–441. - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical