TGF-beta receptors PAR-ticipate in axon formation
- PMID: 20603011
- DOI: 10.1016/j.cell.2010.06.024
TGF-beta receptors PAR-ticipate in axon formation
Abstract
How does a newborn neuron initiate and elaborate an axon? Using cutting-edge approaches, Yi et al. (2010) provide striking evidence that TGF-beta signaling via the Par polarity complex is required for axon formation by neocortical pyramidal neurons.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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TGF-beta signaling specifies axons during brain development.Cell. 2010 Jul 9;142(1):144-57. doi: 10.1016/j.cell.2010.06.010. Cell. 2010. PMID: 20603020 Free PMC article.
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