Comment
doi: 10.1016/j.molcel.2010.06.030.
What the mitochondria see
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- PMID: 20603071
- DOI: 10.1016/j.molcel.2010.06.030
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Comment
What the mitochondria see
Mol Cell.
.
Free article
Abstract
High-Ca(2+) microdomains at ER-mitochondrial junctions have been presumed to exist. Csordás et al. (2010) and Giacomello et al. (2010) report the Ca(2+) dynamics at the outer mitochondrial membrane surface in response to IP(3)-mediated Ca(2+) release and store-mediated Ca(2+) influx with several expected and some unexpected findings.
2010 Elsevier Inc. All rights reserved.
Comment on
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Ca2+ hot spots on the mitochondrial surface are generated by Ca2+ mobilization from stores, but not by activation of store-operated Ca2+ channels.Mol Cell. 2010 Apr 23;38(2):280-90. doi: 10.1016/j.molcel.2010.04.003. Mol Cell. 2010. PMID: 20417605
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Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface.Mol Cell. 2010 Jul 9;39(1):121-32. doi: 10.1016/j.molcel.2010.06.029. Mol Cell. 2010. PMID: 20603080 Free PMC article.
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