Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Jan-Feb;8(1):75-8.
doi: 10.1016/0920-1211(91)90039-i.

Serum folic acid levels in epileptic mothers and their relationship to congenital malformations

Y Ogawa  1 , S Kaneko, K Otani, Y Fukushima
Affiliations

Serum folic acid levels in epileptic mothers and their relationship to congenital malformations

Y Ogawa et al. Epilepsy Res. 1991 Jan-Feb.

Abstract

Folic acid levels during pregnancy and in pre-pregnancy were determined in 51 epileptic mothers and those of matched controls. The serum folic acid (SF) levels of epileptic mothers were significantly lower than those of controls in all study periods. The SF levels of mothers of malformed offspring were significantly lower than those of mothers of normal offspring in the 1st and 2nd trimesters of pregnancy. These results suggest that SF concentrations are implicated in congenital malformations in the offspring of epileptic mothers.

PubMed Disclaimer

Publication types