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. 2010 Aug 1;26(15):1903-4.
doi: 10.1093/bioinformatics/btq304. Epub 2010 Jul 6.

Cloud-Coffee: implementation of a parallel consistency-based multiple alignment algorithm in the T-Coffee package and its benchmarking on the Amazon Elastic-Cloud

Paolo Di Tommaso  1 , Miquel Orobitg, Fernando Guirado, Fernado Cores, Toni Espinosa, Cedric Notredame
Affiliations

Cloud-Coffee: implementation of a parallel consistency-based multiple alignment algorithm in the T-Coffee package and its benchmarking on the Amazon Elastic-Cloud

Paolo Di Tommaso et al. Bioinformatics. .

Abstract

Summary: We present the first parallel implementation of the T-Coffee consistency-based multiple aligner. We benchmark it on the Amazon Elastic Cloud (EC2) and show that the parallelization procedure is reasonably effective. We also conclude that for a web server with moderate usage (10K hits/month) the cloud provides a cost-effective alternative to in-house deployment.

Availability: T-Coffee is a freeware open source package available from http://www.tcoffee.org/homepage.html

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