doi: 10.1016/0014-5793(91)80776-y.
Down-regulation of a kinase defective PKC-alpha
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- PMID: 2060619
- DOI: 10.1016/0014-5793(91)80776-y
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Down-regulation of a kinase defective PKC-alpha
FEBS Lett.
.
Free article
Abstract
A kinase defective mutant of PKC-alpha down-regulates in response to phorbol esters as effectively as the wild-type protein when introduced into COS-1 cells. This demonstrates that intramolecular autophosphorylation is not a prerequisite for down-regulation.
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