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. 2010 Apr-Jun;55(2):151-6.
doi: 10.4103/0019-5154.62751.

Genetics of psoriasis and psoriatic arthritis

Affiliations

Genetics of psoriasis and psoriatic arthritis

Vinod Chandran. Indian J Dermatol. 2010 Apr-Jun.

Abstract

It is well established that psoriasis and psoriatic arthritis (PsA) have a strong genetic component. Recent advances in genetics have confirmed previous associations and new loci have been discovered. However, these loci do not fully account for the high heritability of psoriasis and PsA and therefore many genetic as well as environmental factors remain to be identified. This paper reviews the current status of genetic studies in psoriasis and PsA.

Keywords: Copy number variation; environment; gene; human leucocyte antigen.

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Conflict of interest statement

Conflict of Interest: Nil.

References

    1. Langley RG, Krueger GG, Griffiths CE. Psoriasis: Epidemiology, clinical features, and quality of life. Ann Rheum Dis. 2005;64:18–23. - PMC - PubMed
    1. Zachariae H. Prevalence of joint disease in patients with psoriasis: Implications for therapy. Am J Clin Dermatol. 2003;4:441–7. - PubMed
    1. Wright V, Moll JM. Psoriatic Arthritis. Seronegative polyarthritis. North Holland Publishing Co; 1976. pp. 169–223.
    1. Thomas DC. Overview of genetic epidemiology. Thomas DC Statistical Methods in Genetic Epidemiology. New York: Oxford University Press; 2004. pp. 3–23.
    1. Ashely-Koch A. Determining genetic component of a disease. In: Haines JL, Pericak-Vance M, editors. Genetic analysis of complex diseases. 2nd ed. New Jersey: John Wiley and Sons; 2006. pp. 91–115.