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. 2010 Aug 1;20(15):4693-9.
doi: 10.1016/j.bmcl.2010.04.144. Epub 2010 May 5.

Synthesis, larvicidal activity, and SAR studies of new benzoylphenylureas containing oxime ether and oxime ester group

Ranfeng Sun  1 , Yongqiang Li, Maoyun Lü, Lixia Xiong, Qingmin Wang
Affiliations

Synthesis, larvicidal activity, and SAR studies of new benzoylphenylureas containing oxime ether and oxime ester group

Ranfeng Sun et al. Bioorg Med Chem Lett. .

Abstract

A series of new structural benzoylphenylureas (BPUs) containing oxime ether and oxime ester group were designed and synthesized. The larvicidal activities against Oriental armyworm and mosquito of these benzoylphenylureas were evaluated and the result of bioassay displayed specific structure-activity relationship (SAR). Most of the compounds exhibited excellent larvicidal activities against Oriental armyworm and mosquito. Interestingly, some compounds showed different structure-activity relationship towards diamondback moth, beet armyworm, and corn borer although three tested insects all belong to the same insect order.

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