Development and evaluation of a flocked nasal midturbinate swab for self-collection in respiratory virus infection diagnostic testing
- PMID: 20610685
- PMCID: PMC2937679
- DOI: 10.1128/JCM.02235-09
Development and evaluation of a flocked nasal midturbinate swab for self-collection in respiratory virus infection diagnostic testing
Abstract
We developed and evaluated flocked nasal midturbinate swabs obtained from 55 asymptomatic and 108 symptomatic volunteers. Self-collected swabs obtained from asymptomatic volunteers yielded numbers of respiratory epithelial cells comparable to those of staff-collected nasal (n = 55) or nasopharyngeal (n = 20) swabs. Specific viruses were detected in swabs self-collected by 42/108 (38.9%) symptomatic volunteers by multiplex PCR.
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References
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- Abu-Diab, A., M. Azzeh, R. Ghneim, R. Ghneim, M. Zoughbi, S. Turkuman, N. Rishmawi, A. E. R. Issa, I. Siriani, R. Dauodi, R. Kattan, and M. Y. Hindiyeh. 2008. Comparison between pernasal flocked swabs and nasopharyngeal aspirates for detection of common respiratory viruses in samples from children. J. Clin. Microbiol. 46:2414-2417. - PMC - PubMed
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- Harper, S. A., J. S. Bradley, J. A. Englund, T. M. File, S. Gravenstein, et al. 2009. Seasonal influenza in adults and children—diagnosis, treatment, chemoprophylaxis, and institutional outbreak management: clinical practice guidelines of the Infectious Diseases Society of America. Clin. Infect. Dis. 48:1003-1032. - PMC - PubMed
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