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Case Reports
. 2008 Dec;2(4):305-8.
doi: 10.1007/s12105-008-0088-8. Epub 2008 Oct 22.

Parathyroid adenoma

Jacqueline A Wieneke  1 , Alice Smith
Affiliations
Case Reports

Parathyroid adenoma

Jacqueline A Wieneke et al. Head Neck Pathol. 2008 Dec.
No abstract available

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Fifty-seven year old man with mild hypercalcemia. 99mTc sestamibi scan demonstrates normal uptake by the thyroid gland with a focal area of pronounced uptake on the left (arrow). Over 2 h the thyroid uptake decreased to better reveal the prominent focal area of increased activity in the region of the lower left lobe of the thyroid consistent with parathyroid adenoma
Fig. 2
Fig. 2
Sonographic image in the longitudinal (a) and transverse (b) plane demonstrates a hypoechoic parathyroid adenoma measuring 2.86 × 1.86 × 1.42 cm. Located centrally within the adenoma is an area of decreased echogenicity consistent with cystic degeneration
Fig. 3
Fig. 3
Gross specimen of a cystic parathyroid adenoma. (a) Exterior view shows a smooth surface with minimal hemorrhage and no significant adhesions. The specimen “shelled out” easily. (b) The mass is opened to demonstrate a smooth cyst wall lining
Fig. 4
Fig. 4
The low-power portion of this H&E stained section shows the hypercellular parathyroid adenoma with a cystic lumen indicated by the ** corresponding to the smooth cyst wall in Fig. 3b. High power examination (inset) depicts the proliferative parathyroid tissue to be composed of a population of chief cells. This parathyroid proliferation lacks the normal fat component
Fig. 5
Fig. 5
(a) H&E stained section shows a solid growth pattern interspersed with areas of cystic change (arrows). The cystic spaces are filled with a watery “proteinaceous” fluid as well as red blood cells. (b) A bright, eosinophilic material fills the “follicle-like” spaces (arrows) with peripheral scalloping reminiscent of the colloid-filled follicles seen in thyroid tissue
See this image and copyright information in PMC

References

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    1. Clark PB, Perrier ND, Morton KA. Detection of an intrathymic parathyroid adenoma using single-photon emission CT 99mTc sestamibi scintigraphy and CT. AJR Am J Roentgenol. 2005;184(Suppl 3):S16–8. - PubMed
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