Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1,600 nm
- PMID: 20615044
- DOI: 10.1117/1.3454392
Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1,600 nm
Abstract
We demonstrate a method to estimate the concentrations of water and lipid in scattering media such as biological tissues with diffuse optical spectra acquired over the range of 900 to 1600 nm. Estimations were performed by fitting the spectra to a model of light propagation in scattering media derived from diffusion theory. To validate the method, spectra were acquired from tissue phantoms consisting of lipid and water emulsions and swine tissues ex vivo with a two-fiber probe.
Similar articles
-
Broadband absorption spectroscopy of turbid media using a dual step steady-state method.J Biomed Opt. 2012 Mar;17(3):037009. doi: 10.1117/1.JBO.17.3.037009. J Biomed Opt. 2012. PMID: 22502581
-
Continuous Wave Spectroscopy with Diffusion Theory for Quantification of Optical Properties: Comparison Between Multi-distance and Multi-wavelength Data Fitting Methods.Adv Exp Med Biol. 2016;923:337-343. doi: 10.1007/978-3-319-38810-6_44. Adv Exp Med Biol. 2016. PMID: 27526161
-
Comparison of water and lipid content measurements using diffuse optical spectroscopy and MRI in emulsion phantoms.Technol Cancer Res Treat. 2003 Dec;2(6):563-9. doi: 10.1177/153303460300200608. Technol Cancer Res Treat. 2003. PMID: 14640767
-
Review of tissue simulating phantoms for optical spectroscopy, imaging and dosimetry.J Biomed Opt. 2006 Jul-Aug;11(4):041102. doi: 10.1117/1.2335429. J Biomed Opt. 2006. PMID: 16965130 Review.
-
Coherent two-dimensional optical spectroscopy.Chem Rev. 2008 Apr;108(4):1331-418. doi: 10.1021/cr078377b. Epub 2008 Mar 26. Chem Rev. 2008. PMID: 18363410 Review. No abstract available.
Cited by
-
Tissue diagnosis during colorectal cancer surgery using optical sensing: an in vivo study.J Transl Med. 2019 Oct 2;17(1):333. doi: 10.1186/s12967-019-2083-0. J Transl Med. 2019. PMID: 31578153 Free PMC article.
-
A linear gradient line source facilitates the use of diffusion models with high order approximation for efficient, accurate turbid sample optical properties recovery.Biomed Opt Express. 2014 Sep 16;5(10):3628-39. doi: 10.1364/BOE.5.003628. eCollection 2014 Oct 1. Biomed Opt Express. 2014. PMID: 25360378 Free PMC article.
-
Quantitative short-wave infrared multispectral imaging of in vivo tissue optical properties.J Biomed Opt. 2014 Aug;19(8):086011. doi: 10.1117/1.JBO.19.8.086011. J Biomed Opt. 2014. PMID: 25120175 Free PMC article.
-
Method for coregistration of optical measurements of breast tissue with histopathology: the importance of accounting for tissue deformations.J Biomed Opt. 2019 Jul;24(7):1-12. doi: 10.1117/1.JBO.24.7.075002. J Biomed Opt. 2019. PMID: 31347338 Free PMC article.
-
Photoacoustic measurement of the Grüneisen parameter of tissue.J Biomed Opt. 2014 Jan;19(1):17007. doi: 10.1117/1.JBO.19.1.017007. J Biomed Opt. 2014. PMID: 24474512 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources