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Meta-Analysis
. 2010 Sep 1;26(17):2190-1.
doi: 10.1093/bioinformatics/btq340. Epub 2010 Jul 8.

METAL: fast and efficient meta-analysis of genomewide association scans

Cristen J Willer  1 , Yun Li, Gonçalo R Abecasis
Affiliations
Meta-Analysis

METAL: fast and efficient meta-analysis of genomewide association scans

Cristen J Willer et al. Bioinformatics. .

Abstract

Summary: METAL provides a computationally efficient tool for meta-analysis of genome-wide association scans, which is a commonly used approach for improving power complex traits gene mapping studies. METAL provides a rich scripting interface and implements efficient memory management to allow analyses of very large data sets and to support a variety of input file formats.

Availability and implementation: METAL, including source code, documentation, examples, and executables, is available at http://www.sph.umich.edu/csg/abecasis/metal/.

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