An IL-1beta-dependent switch in innate mucosal immunity?
- PMID: 20620939
- DOI: 10.1016/j.immuni.2010.06.012
An IL-1beta-dependent switch in innate mucosal immunity?
Abstract
The mechanisms that guide the development of mucosal-associated innate lymphoid cells (ILCs) producing IL-17, IL-22, and IFN-gamma are the subject of intense interest. In this issue of Immunity, Hughes et al. (2010) identify a new role for IL-1beta in regulating an IL-22-producing ILC.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue.Immunity. 2010 Jun 25;32(6):803-14. doi: 10.1016/j.immuni.2010.06.007. Immunity. 2010. PMID: 20620944 Free PMC article.
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